Overview of Zoltero
Zoltero is an anticancer medication containing Zoledronic acid, a bisphosphonate. It is a prescription drug used in the treatment of certain conditions.
- Paget’s Disease of Bone
Indicated to adult (male/female) patients with Paget’s disease of bone who are symptomatic, with elevations in serum alkaline phosphatase of two times, or who are at risk of developing disease-related complications.
- Osteoporosis In Men
Indicated to adult (male) patients with evidence of increased bone mass with osteoporosis.
- Glucocorticoid-Induced Osteoporosis
Indicated to adult (male/female) patients with glucocorticoid-induced osteoporosis who are thought to stay on glucocorticoids for at least a year.
Other than this, Zoltero is also used in the prevention of osteoporosis in postmenopausal women and glucocorticoid-induced osteoporosis in both men and women. The active ingredient of Zoltero is Zoledronic acid which is a nitrogen-containing bisphosphonate. Its inactive ingredients are sodium citrate and mannitol. Zoltero is available in the form of a sterile lyophilized injection (as a vial) in the strength of 4 mg for intravenous infusion. Zoledronic acid works by lowering the levels of calcium in the blood (mostly caused by cancer).
Below are some significant interactions mentioned. Be sure to read them before the administration of your first Zoltero dose.
Medicine interactions: Deferasirox, Immunosuppressants, Etelcalcetide, Methotrexate, and Torsemide can cause severe to moderate interactions with the ingredients present in Zoltero injection including Zoledronic acid. Some other drugs that contain these compounds as active ingredients can also show significant interactions with Zoltero injection. Make sure to inform your healthcare provider if you consume any of these medicines or any other regimens.
Disease interactions: Kidney impairment, asthma, and hypocalcemia can cause severe to moderate interactions with the ingredients present in Zoltero injection including Zoledronic acid. Some other conditions associated with the cause or consequence of these diseases can also show significant interactions with Zoltero injection. Make sure to inform your healthcare provider if you are suffering from any such diseases.
Food interactions: No clinically significant food interactions are known. However, do not consume alcohol during the course of Zoltero injection to avoid drowsiness. For other concerns related to your diet during the therapy, make sure to consult your medical team.
Q1- What is Zoltero?
A- Zoltero (Zoledronic acid) Injection is used in the treatment of osteoporosis in postmenopausal women to reduce the incidence of hip, vertebral and non-vertebral fractures.
Q2- What are the storage conditions for Zoltero?
A- Store Zoltero (Zoledronic acid) Injection at room temperature (10-30°C) in the same container. Keep it away from the reach of children and pets. Protect the medicine from direct heat, light, and moisture.
Q3- What are the common side effects of Zoltero?
A- Some of the common side effects of Zoltero (Zoledronic acid) Injection are bone pain, vomiting, difficulty in swallowing, fatigue, constipation, nausea, sore throat, etc. There can be other side effects also. Make sure to contact your healthcare professional to get the needed help.
Q4- What is the composition and strength of Zoltero?
A- The active ingredient of Zoltero injection is Zoledronic acid. This medicine is available in the strength of 4 mg in the form of an injection.
Q5- What are self-care tips?
A- Eat a healthy diet with plenty of calcium-containing foods. Avoid the consumption of alcohol.
Q6- How should I take this medicine?
A- Your healthcare provider will decide your dose strength and duration, and will give you this injection. Do not self administer.
Q7- Name some alternate brands of Zoltero (Zoledronic acid) Injection?
A- Some of the substitutes for Zoltero (Zoledronic acid) Injection are:
- Zunitra 4mg Injection
- Zoldron Injection
- Zoleget Injection
- Sibazol 4mg Injection
- Zolic 4mg Injection
Q8- What are the warnings and precautionary steps?
A- Administer Zoltero (Zoledronic acid) Injection cautiously in case you:
- Are pregnant
- Are breastfeeding
- Have heart disease
- Have liver disease
- Have kidney disease
- Have an allergy
Q9- Is it safe to take Zoltero during pregnancy or breastfeeding?
A- During pregnancy or breastfeeding, Zoltero (Zoledronic acid) Injection should be taken only if the healthcare provider prescribes after discussing the risks and benefits of taking this medicine.
Q10- Is it safe to drive after taking Zoltero?
A- After taking Zoltero (Zoledronic acid) Injection, do not drive or operate heavy machinery if side effects like dizziness or lack of concentration occur.