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Composition : Enzalutamide

Manufacturer : Astellas

Indication : Prostate cancer

Packaging : Bottle

Dosage Form : Capsule




Enzalutamide is the active ingredient present in the medicine named Xtandi and it belongs to a family of drugs known as androgen receptor inhibitors. Xtandi is available in the form of a capsule with a strength of 40mg. This tablet is indicated for the treatment of Prostate cancer and it works by inhibiting the effect of testosterone. Xtandi (Enzalutamide) also helps in preventing the spread of cancerous cells in the body. 

Enzalutamide is an androgen receptor inhibitor that affects a variety of signaling pathways. It possesses the ability to prevent androgen binding to its receptor, nuclear translocation of the receptor, and subsequent DNA interaction. Take Xtandi tablet according to your dosing schedule to get the most benefit. 


Interactions can occur if you use some other medicinal products while receiving treatment with an Xtandi tablet. Always inform your healthcare professional or medical practitioner about your previous and current health condition to avoid some major side effects.

Medicine interactions:- abemaciclib, bedaquiline, cabozantinib, ceritinib, daclatasvir, elvitegravir, fedratinib, etc are the drugs that may increase or decrease the serum concentration of Enzalutamide. It is better to avoid the use of Xtandi tablets in combination with these drugs because it can lead to adverse events and decrease the effectiveness of this therapy.

Disease interactions:- the use of Xtandi tablets may interact with various other diseases such as renal impairment and seizures. In order to avoid these abnormalities, extreme caution and monitoring of the clinical condition are recommended in patients while receiving treatment with Xtandi (Enzalutamide).

Food interactions:- Avoid the use of such products that can interact with Xtandi (Enzalutamide) because it can cause a serious allergic reaction and it includes side effects like – bleeding, Loss of appetite, bloating, joint pain, drowsiness, vomiting, fatigue, skin rash, etc. 

Alcohol interactions:- consuming alcohol while receiving treatment with Xtandi (Enzalutamide) tablet may increase the risk of excessive dizziness and drowsiness in patients. It is better to avoid the consumption of alcohol and consult with your medical professional or physician before consuming it.

Q1. What is Xtandi (Enzalutamide)?

Ans. Xtandi capsule is used in the treatment of Prostate cancer. This medication belongs to the class of medications known as antineoplastic endocrine therapies and it helps in blocking the effect of testosterone. 

Q2. What are the side effects?

Ans. Some common side effects are:- nausea, abdominal pain, headache, weakness, loss of appetite, fatigue, high blood pressure, fever, etc.  

Q3. How to take this medicine?

Ans. Take this medicine orally once a day with food or without food. Swallow the whole capsule with a glass of water and take it regularly at the same time every day. Do not take this medicine in the wrong way as it may lead to some severe side effects. It is important to take this medicine as prescribed by your doctor. 

Q4. Can I take this medicine during pregnancy? 

Ans. Do not use Xtandi capsules if you are pregnant or planning to become pregnant. This medication can cause harm to the unborn baby.

Q5. How does Xtandi (Enzalutamide) work?

Ans. Xtandi capsules are used to treat CRPC (castrate-resistant prostate cancer, a stage where prostate cancer keeps growing) that has spread to other parts of the body. It prevents the action of androgens.

Q6. What are the warnings and precautions?

Ans. Before starting treatment with Xtandi capsules, please inform your doctor about your previous medical history.

  • Close monitoring of kidney function is required during treatment with this medicine. 
  • This medication may increase the risk of falls, fractures, and serious injuries.
  • Do not use this medicine if you are allergic to Enzalutamide.
  • Do not chew or open the capsule. 

 Q7. What are the storage conditions?

Ans. Store this medicine at room temperature. Keep it away from direct heat and light. Please consult your pharmacist or doctor for more details regarding the Xtandi (Enzalutamide).

Q8.  Can I drive after taking this medicine?

Ans. Xtandi (Enzalutamide) capsules may cause dizziness in some patients. Do not drive if you experience any symptoms of dizziness because it may affect your ability to drive.

Q9. What happens if I miss a dose? 

Ans. If you miss a scheduled dose of Xtandi capsules, contact your doctor immediately. Do not stop or change your dosing schedule without taking suggestions from your doctor.  

Q10. What should I avoid while receiving this medication? 

Ans. Avoid contact with people who have infections and avoid driving or operating heavy machinery. Follow your doctor’s instructions and restrictions about any food and other activities. 

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