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Composition : Abiraterone Acetate

Manufacturer : Cipla

Indication : Prostate cancer

Packaging : Bottle

Dosage Form : Tablet




Abiraterone acetate is an active compound present in the medication named Xbira and it belongs to a family of medications known as androgen biosynthesis inhibitors. Xbira is available in the form of a tablet with a strength of 250mg. This tablet is prescribed for the treatment of Prostate cancer and it works by blocking the activity of an enzyme (CYP17) that is responsible for the progression of androgen. Abiraterone acetate helps in lowering the level of PSA (Prostate-specific antigen) and more specifically it also helps in decreasing the serum levels of testosterone and other androgens. 

Xbira (Abiraterone acetate) is an orally administered medication and it is consumed with a glass of water, follow up on your regular dosing schedule prescribed by your health professional. The covalent binding mechanism inhibits CYP17A1 in a selective and irreversible manner. The enzyme CYP17A1 catalyzes the manufacture of androgen and is found in abundance in testicular, adrenal, and prostatic tumor tissue.


Using Xbira tablets in combination with other medical or herbal products, causing severe adverse reactions. Talk to your medical professional about the possibility of interactions with drugs, disease, food, and alcohol while receiving therapy with Xbira (Abiraterone acetate) tablet.

Medicine interactions:- amisulpride, apalutamide, berotralstat, carbamazepine, dolasetron, fingolimod, hydrocodone, etc. are the drugs that may increase or decrease the serum concentration and metabolism when used with Abiraterone acetate. Avoid the use of Xbira tablets in combination with these medications because it can lead to adverse events and lowers the effectiveness of the treatment.

Disease interactions:- use of Xbira tablets may interact with various other diseases such as renal impairment and cardiovascular disease. In order to avoid these abnormalities, extreme caution and monitoring of the clinical condition are recommended in patients while receiving therapy with Xbira (Abiraterone acetate).

Food interactions:- Avoid the use of such products that can interact with Xbira (Abiraterone acetate) because it can cause allergic reactions and it includes side effects like – bleeding, fainting, bloating, muscle pain, drowsiness, vomiting, hot flashes, skin rash, etc. 

Alcohol interactions:- consuming alcohol while receiving treatment with Xbira (Abiraterone acetate) tablet may increase the risk of dizziness and drowsiness in some patients. It is better to avoid the consumption and consult it with your healthcare professional before consuming.

Q1- What is Xbira (Abiraterone Acetate)?

A- Xbira (Abiraterone Acetate) tablet is an anti-cancer medication. It is used in the  treatment of male patients with cancer of the Prostate Gland. It should not be taken on an empty stomach.

Q2- What are the storage conditions for Xbira?

A- Store Xbira (Abiraterone Acetate) tablets at room temperature. Don’t store above 30°C (86°F). Keep it away from the reach of children and pets.

Q3- What are the common side effects of Xbira?

A- Some of the common side effects of Xbira (Abiraterone Acetate) tablets are vomiting, fever, nausea, fatigue, high blood pressure, cough, diarrhea, anemia, urine infection, etc. Note that there can be other side effects also. It is advised to seek medical attention if side effects occur and disturb your daily routine.

Q4- What is the composition and strength of Xbira?

A- The active ingredient of Xbira is Abiraterone Acetate. It is available in the form of tablets (oral administration) in the strength of 250 mg.

Q5- How does Xbira (Abiraterone Acetate) tablet work?

A- Xbira comprises Abiraterone Acetate. Abiraterone is the active metabolite of abiraterone acetate that inhibits CYP17A1. Abiraterone acetate suppresses the production of androgens. It decreases the production of testosterone in the body and is therefore used with other medications to treat prostate cancer in men.

Q6- How should I take this medicine?

A- Swallow this tablet with water. Take it exactly in the same dose and duration as prescribed by your doctor. Do not crush or chew the tablet.

Q7- What should be done in cases of overdose and missed dose?

A- In case of overdose, it is advised to seek emergency attention from a medical practitioner. However, in case of a missed dose, you can take the dose as soon as you remember. It is advised not to double the dose strength to catch up.

Q8- What are the warnings and precautionary steps?

Warning: Before the consumption of the Xbira (Abiraterone Acetate) tablets, make sure to talk to the medical practitioner about

  • Your current medical condition
  • Your medical history
  • Any known allergy or disease you have or ever had
  • Contraception 

Precautions: Avoid

  • Drinking alcohol
  • Smoking
  • Driving or operating machines

Q9- Is it safe to take Xbira (Abiraterone Acetate) tablet during pregnancy or breastfeeding?

A- Xbira (Abiraterone Acetate) tablet is unsafe for use during pregnancy or breastfeeding. 

Q10- Is it safe to drive after taking Xbira (Abiraterone Acetate) tablet?

A- It is advised to not drive or operate heavy machinery after consuming this medicine because Xbira (Abiraterone Acetate) tablet may cause dizziness or may affect your ability to concentrate.

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