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Rituxan

Composition : Rituximab

Manufacturer : Genentech

Indication : Lymphoma

Packaging : vial

Dosage Form : Injection

Category:
Description

Description

Overview of Rituxan 

Rituxan is a formulation of Rituximab, a monoclonal anti-CD20 antibody. It is a prescription drug used in the treatment of a number of conditions concerning certain types of cancers. The active ingredient of Rituxan injection is Rituximab. The below-mentioned indications are relevant to the use of Rituxan injection. 

  • Indicated as a single agent to patients diagnosed with Relapsed, low-grade or follicular, CD20-positive, B-cell Non-Hodgkin lymphoma. 
  • Indicated in combination with first-line chemotherapy to treatment-naive patients diagnosed with CD20-positive, B-cell Non-Hodgkin lymphoma. 
  • Indicated as a single agent to patients diagnosed with non-progressing, low-grade, CD20-positive, B-cell Non-Hodgkin lymphoma after first-line chemotherapy with cyclophosphamide, vincristine, and prednisone. 
  • Indicated in combination with drugs including doxorubicin, cyclophosphamide, vincristine, and prednisone to patients diagnosed with diffuse large B-cell, CD20-positive Non-Hodgkin lymphoma.
  • Indicated in combination with fludarabine and cyclophosphamide to treatment-naive patients diagnosed with Chronic Lymphocytic Leukemia. 
  • Indicated in combination with methotrexate to patients diagnosed with moderately to severely active rheumatoid arthritis with evidence of response to one or more TNF antagonist-based therapies. 
  • Indicated in combination with glucocorticoids to patients diagnosed with Granulomatosis with Polyangiitis and Microscopic Polyangiitis. 
  • Indicated to patients diagnosed with moderate to severe pemphigus Vulgaris.

Interactions

Before starting your therapy with Rituxan (Rituximab) injection, be sure to know the following interactions: 

Drug Interactions: Adalimumab, infliximab, natalizumab, ponesimod, sarilumab, tocilizumab, voclosporin, fingolimod, deferiprone, baricitinib, and certolizumab are some of the known medicines that are thought to interact with the ingredients of Rituxan injection including Rituximab. 

Disease Interactions: Renal impairment, infections, bone marrow suppression, autoimmune diseases, cardiac dysfunction, hepatitis B, and tumor lysis syndrome are some of the known diseases that are thought to interact with the ingredients of Rituxan injection including Rituximab. 

Food Interactions: There are no clinically significant food interactions (concerning the use of Rituxan injection) available. Please consult your medical team and chart out a diet plan for your treatment period. 

Alcohol Interactions: It is not known whether alcohol causes interactions with the ingredients of Rituxan injection or not. Please consult your medical team to learn about the possible risks associated with the consumption of alcoholic drinks. 

Q1- What is Rituxan?

A- Rituxan (Rituximab) Injection is used in the treatment of Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, Rheumatoid Arthritis, Granulomatosis with Polyangiitis, Idiopathic Thrombocytopenic Purpura, Pemphigus Vulgaris, Myasthenia Gravis, and Epstein–Barr virus-positive Mucocutaneous Ulcers. 

Q2- What are the storage conditions for Rituxan?

A- Store Rituxan (Rituximab) Injection at room temperature in the same container. Protect from light and keep it away from the reach of children.

Q3- What are the common side effects of Rituxan?

A- Some of the side effects of Rituxan (Rituximab) Injection are diarrhea, nausea, abdominal pain, vomiting, fever, blurred vision, anxiety, etc. There can be other side effects also. Therefore, make sure to contact a medical practitioner if side effects occur or last longer than usual.

Q4- What is the composition and strength of Rituxan?

A- The active ingredient of Rituxan is Rituximab. It is available in the form of an injection in the strengths of 100, mg and 500 mg.

Q5- What are self-care tips?

A- Do not skip a dose. Also, make sure to consult your healthcare provider if side effects occur.

Q6- How should I take this medicine?

A- A medical practitioner will give you this injection. It is given in a vein as an infusion. Do not self administer.

Q7- What should be done in cases of overdose and missed dose?

A- It is advisable not to miss a dose. If you miss a scheduled dose of this medicine, contact your doctor immediately. Also, in case of overdose, emergency medical attention is a must.

Q8- What are the warnings and precautionary steps?

A- Before the consumption of this medicine, it is advised to contact a healthcare professional regarding:

  • Your medical history 
  • Your medical condition
  • Any scheduled vaccine
  • Any allergy you have or ever had
  • Any disease you have or ever had
  • Medicines/supplements you already take

Q9- Is it safe to take Rituxan (Rituximab) Injection during pregnancy or breastfeeding?

A- Avoid this medication at the time of pregnancy. Also, during breastfeeding, take this medicine only if the healthcare provider prescribes it after discussing the risks and benefits beforehand.

Q10- Is it safe to drive after taking Rituxan?

A- It is advisable not to drive or operate heavy machinery if you feel unwell after taking Rituxan (Rituximab) Injection.

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