Overview of Perfecine
Perfecine is a formulation of Pirfenidone, an orally active small molecule drug. This medication is available by prescription for the treatment of patients diagnosed with idiopathic pulmonary fibrosis (a rare and progressive disorder of the respiratory system). The regimen is available in the form of tablets for oral use by Arechar Healthcare in a fixed strength of 200 mg. Perfecine (Pirfenidone) tablets belong to the categories of drugs known as antifibrotic agents and antioxidants. This medicine comprises anti-inflammatory properties and is associated with gastrointestinal adverse effects. It is prescribed for use usually with food to decrease the probability of side effects. Perfecine tablets should not be administered in patients who are allergic or hypersensitive to any of the ingredients present in the regimen.
The active ingredient of Perfecine tablets is Pirfenidone. Its inactive ingredients are titanium dioxide, microcrystalline cellulose, povidone, magnesium stearate, polyvinyl alcohol, iron oxide, croscarmellose sodium, polyethylene glycol, talc, and colloidal anhydrous silica.
The following elements might interact with the ingredients of Perfecine (Pirfenidone) tablets. Be sure to inform your medical team about your medical history in order to prevent further complications.
Drug Interactions: Ciprofloxacin, teriflunomide, amiodarone, rifampicin, leflunomide, vemurafenib, and enoxacin are some of the known medications that show significant interactions with the active and inactive ingredients of Perfecine (Pirfenidone) tablets. If you administer any of these drugs already, make sure to inform your medical team about them. Dose adjustments may be needed in some cases to reduce the consequences of interactions.
Disease Interactions: Hepatic impairment, smoking, and renal impairment are a few conditions that may show significant interactions with the active and inactive ingredients of Perfecine (Pirfenidone) tablets. If you are addicted to smoking or are suffering from any of the mentioned diseases, make sure to inform your medical team about it. Dose adjustments may be needed in some cases to reduce the consequences of interactions.
Food Interactions: Taking Perfecine (Pirfenidone) tablets with food may reduce the possibility of adverse events like nausea and vomiting, and dizziness. There is clear evidence of food impacting the bioavailability of Pirfenidone also.
Q1. What is Perfecine (Pirfenidone)?
Ans. Perfecine is an effective regimen that is prescribed for the treatment of IPF (Idiopathic pulmonary fibrosis). Perfecine (Pirfenidone) medication helps in reducing the effect like – swelling in the lungs to make breathing easier. During treatment with Perfecine, your healthcare provider may monitor your liver function regularly.
Q2. What are the side effects of Perfecine (Pirfenidone)?
Ans. Some common and possible side effects of Perfecine tablets are – skin sensitivity to sunlight, nausea, tiredness, diarrhea, indigestion, loss of appetite, headache, difficulty sleeping, dizziness, sleepiness, changes in taste, throat infection, shortness of breath, cough, vomiting, bloating, abdominal pain and discomfort, heartburn, constipation, etc.
Q3. How should I take Perfecine (Pirfenidone)?
Ans. Perfecine (Pirfenidone) is available in the form of oral-use tablets. Administer the recommended dosage of this tablet orally with a glass of water. Do not crush, chew or break the Perfecine tablet.
Q4. What happens if I miss the dose of Perfecine (Pirfenidone)?
Ans. Make sure to take the dose of Perfecine (Pirfenidone) tablet as prescribed by your healthcare provider, in case you missed the dose contact your medical practitioner.
Q5. What should I avoid during treatment with Perfecine (Pirfenidone)?
Ans. The use of Perfecine (Pirfenidone) tablets increases the risk of severe sunburn in some patients, it is advised to avoid exposure to sunlight. Also, avoid smoking because it reduces the effect of the treatment with Perfecine tablets.
Q6. What are the warnings and precautions of Perfecine (Pirfenidone)?
Ans. Before starting therapy with Perfecine (Pirfenidone) tablets, talk about all the benefits and risks with your physician or medical practitioner. Following are the warnings and precautions of Perfecine tablet
- Avoid performing any activity that requires alertness and concentration while receiving treatment with Perfecine (Pirfenidone) tablets.
- Do not use Perfecine if you are allergic to Pirfenidone.
- Regular monitoring of the clinical condition is recommended in some patients during treatment with Perfecine (Pirfenidone) tablets.
Q7. Can I consume alcohol while receiving therapy with Perfecine (Pirfenidone)?
Ans. Avoid consuming alcohol while receiving therapy with Perfecine (Pirfenidone) because alcohol and the ingredients of Perfecine can interact with each other.
Q8. Is it safe to take Perfecine (Pirfenidone) during pregnancy and breastfeeding?
Ans. Perfecine tablets are not recommended for use in pregnancy and breastfeeding. Consult with your experienced physician or healthcare provider before starting treatment.
Q9. Can I drive after taking Perfecine (Pirfenidone)?
Ans. Perfecine tablets may cause drowsiness and blurred vision in patients. It is advisable to avoid driving and other tasks that require attention and concentration while receiving therapy with Perfecine (Pirfenidone).
Q10. What are the storage conditions of Perfecine (Pirfenidone)?
Ans. Store Perfecine (Pirfenidone) tablets at room temperature and keep them away from direct heat and light. Protect Perfecine tablets from getting moist.