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Gefitero

Brand name – Gefitero

Generic name – Gefitinib

Manufacturer – Hetero Drugs Ltd

Strength – 250 mg

Dosage – Oral (tablet)

Packaging – Strip

Indication – Lung cancer

Category:
Description

Description

Overview

Gefitinib is an active agent present in the medication named Gefitero and it belongs to an EGFR (epidermal growth factor receptor) tyrosine kinase inhibitor. Gefitero is available in the form of a tablet with a strength of 250mg and it is prescribed for the treatment of Non-small cell lung cancer (NSCLC). This tablet helps in preventing the growth of cancer cells by inhibiting the activity of an abnormal protein. Administer Gefitero (Gefitinib) tablet orally with a glass of water and take this anti-cancer formulation as prescribed by your medical professional.

Several tyrosine kinases linked with transmembrane cell surface receptors, including those associated with the epidermal growth factor receptor, are phosphorylated intracellularly by Gefitinib. Many normal and malignant cells express EGFR on their cell surfaces. Gefitinib is the only selective EGFR (epidermal growth factor receptor) tyrosine kinase inhibitor, commonly known as Her1 or ErbB-1. The downstream signaling cascades are also suppressed when the EGFR tyrosine kinase is inhibited, resulting in decreased malignant cell growth.

Interactions

Other medicines may interact with Gefitero, causing major adverse reactions. During your treatment with Gefitero (Gefitinib) tablet, talk with your healthcare professional about the possibility of interactions with other medications, diseases, foods, and alcohol.

Medicine interactions:– mipomersen, teriflunomide, ozanimod, aminolevulinic acid, leflunomide, thioridazine, etc are drugs that may interact with Gefitero (Gefitinib) tablet and it decreases the excretion rate and therapeutic efficacy of this cancer-fighting medication. 

Disease interactions:– liver disease, GI disorders, dermatologic toxicities, pulmonary toxicity, ocular disorders, renal dysfunction, etc are the disease that may interact majorly or moderately with Gefitero (Gefitinib) tablet, and close monitoring of the health condition is recommended in patients. 

Food interactions:– Avoid the use of products that can interact with Gefitero (Gefitinib) tablet because it may cause allergic reactions and it includes side effects such as – allergic skin reaction, headache, diarrhea, constipation, eye irritation or pain, vomiting, loss of appetite, dehydration, indigestion, etc.

Alcohol interactions:- consuming alcohol while receiving treatment with Gefitero (Gefitinib) tablets may increase the risk of dizziness, severe lightheadedness, and drowsiness in patients. It is better to avoid the consumption of alcohol and other alcoholic beverages and consult with your health professional before consuming them.

Q1- What is the use of Gefitero (Gefitinib) tablet?

A- Gefitero tablet is an anticancer medicine. It is used to treat non-small cell Lung cancer (NSCLC) in patients who have EGFR (epidermal growth factor receptor) genes.

Q2- What are the possible side effects of Gefitero (Gefitinib) tablet?

A- Some of the side effects of Gefitero tablets are diarrhea, dry skin, skin rash, nausea, dizziness, weight loss, weakness, etc. It is advised to consult your healthcare professional if you experience side effects after taking this medicine (these/others).

Q3- How does Gefitero (Gefitinib) work?

A- The active ingredient of Gefitero is Gefitinib. It is the first selective inhibitor of epidermal growth factor receptor’s (EGFR) tyrosine kinase domain. Therefore, it inhibits EGFR tyrosine kinase by binding to the adenosine triphosphate-binding site of the enzyme.

Q4- What is the composition and strength of Gefitero?

A- The active ingredient of Gefitero is Gefitinib. This medication is available in the form of tablets in the strength of 250 mg.

Q5- What are the storage conditions for Gefitero (Gefitinib)?

A- Gefitero tablet should be stored at room temperature (10-30°C). It is advised to protect this medicine from direct heat, light, and moisture.

Q6- What are the necessary precautions?

A- Tell your doctor beforehand if you:

  • Are allergic to any of the ingredients of Gefitero
  • Are pregnant or breastfeeding
  • Have or ever had any disease (liver, kidney, heart, etc)

Q7- How should I take Gefitero (Gefitinib)?

A- Take (swallow with water) this tablet as a whole. Do not try to break or chew it. Also, do not increase or decrease the dose strength, unless your doctor tells you. 

Q8- Is it safe to drive after taking Gefitero (Gefitinib)?

A- Avoid driving and operating heavy machines if you feel unwell after taking a Gefitero tablet as this medicine may affect your ability to concentrate. 

Q9- Is it safe to take Gefitero (Gefitinib) during pregnancy or breastfeeding?

A- During pregnancy or breastfeeding, it is advised to consult a medical practitioner before taking any new medicine. Therefore, make sure to do so. Also, make sure to discuss the risks and benefits of taking this medicine.

Q10- What should I avoid while consuming this tablet?

A- While consuming this medicine, make sure to avoid:

  • Drinking alcohol
  • Smoking
  • Eating smoked fish and undercooked eggs
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