Description

Overview of Aromasin 

Aromasin is an anticancer formulation of a strong agent namely Exemestane. This is a prescription medication used in the treatment of patients diagnosed with estrogen-receptor positive early breast cancer. It is specifically used to treat postmenopausal women who have received two to three years of tamoxifen. Such patients are prescribed Aromasin for completing the five years of adjuvant hormonal therapy. It is also indicated for the treatment of women who are diagnosed with disease progression after tamoxifen therapy. Aromasin is available in the form of tablets in the fixed strength of 25 mg for oral use only by Pfizer. 

The active ingredient of Aromasin is Exemestane. It belongs to the category of regimens known as aromatase inhibitors. Aromasin is also known to be an antiestrogen. Being an oral steroidal compound, it works by lowering the estrogen level in the body by blocking its synthesis. This process leads to the slow growth of cancer cells. The inactive ingredients of the Aromasin tablets are mannitol, polysorbate 80, colloidal silicon dioxide, sodium starch glycolate, simethicone, polyethylene glycol 6000, magnesium stearate, microcrystalline cellulose, sucrose, magnesium carbonate, polyvinyl alcohol, methylparaben, titanium dioxide, hypromellose, and crospovidone. 

Interactions

Drugs interact differently from one person to the other. However, below-mentioned are certain standard interactions associated with the administration of Aromasin (Exemestane) tablets:

Drug Interactions: Aspirin, loratadine, ascorbic acid, everolimus, albuterol, venlafaxine, and denosumab are thought to cause significant interactions with the ingredients present in Aromasin tablets including Exemestane. Thorough and routine assessment of body function may be done by the healthcare team during Aromasin therapy. Also, you may need certain dose modifications to decrease the possibility and effects of interactions. 

Disease Interactions: Osteoporosis and vitamin D deficiency are thought to cause significant interactions with the ingredients present in Aromasin tablets including Exemestane. A thorough assessment of vitamin D may be initiated prior to the administration of the first dose. In women with Osteoporosis, BDM loss may be monitored. Also, you may need certain dose modifications to decrease the possibility and effects of interactions. 

Food Interactions: Administration of Aromasin (Exemestane) tablets should be done with food (after a meal) as per the recommendations by the manufacturer. 

Q1- What is Aromasin (Exemestane)?

A- Aromasin (Exemestane) is an anti-cancer medication. It is used in the treatment of Breast cancer. It is a kind of endocrine therapy known as an aromatase inhibitor.

Q2- What are the storage conditions for Aromasin?

A- Store Aromasin (Exemestane) tablets at room temperature away from light and moisture. Do not store in the bathroom. Keep it away from the reach of children and pets.

Q3- What are the common side effects of Aromasin?

A- Some of the common side effects of Aromasin (Exemestane) tablets are tiredness, unusual sweating, nausea, diarrhea, hot flashes, hair loss, unusual tiredness, dark urine, yellowing eyes/skin, confusion, coughing up blood, etc. There can be other side effects also. Make sure to contact your healthcare professional to get the needed help.

Q4- What is the composition and strength of Aromasin?

A- The active ingredient of Aromasin tablet is Exemestane. It is available in the strength of 25mg in the form of tablets for oral administration.

Q5- Name some alternate brands of Aromasin (Exemestane) tablet?

A- Following are the substitutes for Aromasin (Exemestane) tablet:

• Arimidex
• Femara

Q6- How should I take this medicine?

A- Take Aromasin (Exemestane) tablet exactly in the same dose strength and duration as the medical practitioner prescribes. Do not skip a dose or overdose. Also, do not change the dose strength unless the medical professional tells you.

Q7- What should be done in cases of overdose and missed dose?

Overdose: In case of overdose, seek emergency medical attention to get needed support.
Missed dose: In case you miss a dose, take the dose as soon as you remember if it is not already the time for your next scheduled dose. Also, be sure to call your healthcare provider for the same. Do not double the dose to catch up with the missed dose.

Q8- What are the warnings and precautionary steps?

A- Before taking Aromasin (Exemestane) tablet, make sure to tell your doctor about:

• Your medical history
• Your current medical condition 
• The medicines you take (including supplements)
• Any disease you have like kidney disease, liver disease, etc. 

Q9- Is it safe to take Aromasin (Exemestane) tablets during pregnancy or breastfeeding?

A- During pregnancy or breastfeeding, take Aromasin (Exemestane) tablet only if the healthcare provider prescribes after discussing the risks and benefits of taking this medicine.

Q10- Is it safe to drive after taking Aromasin?

A- After taking Aromasin (Exemestane) tablet, do not drive or operate heavy machinery if side effects like dizziness or lack of concentration occur.