Overview of Abirapro
Abirapro is a formulation of Abiraterone Acetate. It is an anti-cancer regimen. The drug is prescribed for the treatment of adult patients diagnosed with metastatic castration-resistant prostate cancer and metastatic high-risk castration sensitive prostate cancer. The safety and efficacy of Abirapro have not been established in females and children. It is available in the form of tablets by Glenmark Pharmaceuticals Ltd in the fixed strength of 250 mg indicated for oral administration only. Abirapro tablets are generally prescribed by the doctor to patients who are not responding to other therapies for Prostate Cancer. It is also used in the treatment of cancer of the prostate gland that has spread to other parts of the body.
The active ingredient of Abirapro tablets is Abiraterone Acetate. It belongs to the category of antiandrogens. The compound is also an orally active inhibitor of the steroidal enzyme CYP17A1. Abirapro selectively works by inhibiting CYP17A1, an enzyme that is responsible for the catalysis of biosynthesis of androgen. The regimen tends to decrease the serum levels of testosterone along with certain other androgens. The inactive ingredients of Abirapro tablets are colloidal silicon dioxide, lactose monohydrate, microcrystalline cellulose, sodium lauryl sulfate, povidone, magnesium stearate, and croscarmellose sodium.
There are certain elements that show interaction with Abiraterone Acetate during Abirapro therapy.
Drug Interactions: Patients who are already administering Carbamazepine, Loperamide, Tamoxifen, Leflunomide, Rifampicin, Edoxaban, Fosphenytoin, and/or Oxycodone should be cautious and make the doctor aware of the drugs they already consume. Regimens containing these drugs can interact with the Abiraterone Acetate and the inactive ingredients of Abirapro tablets. You may require certain dose adjustments during the therapy to hinder such interactions.
Disease Interactions: Patients who are already suffering from Hepatic Impairment or/and Cardiovascular Diseases should be cautious and make the doctor aware of the medical condition. These diseases can interact with the Abiraterone Acetate and the inactive ingredients of Abirapro tablets. You may require certain dose adjustments during the therapy to hinder such interactions.
Food Interactions: A herb, known as St. John’s Wort, can interact with Abiraterone Acetate and the inactive ingredients of Abirapro tablets. It can lead to an increase in the serum labels of Abiraterone by inducing CYP3A4. Your doctor may, therefore, recommend you not to consume any food item containing this ingredient.
Q1- What is Abirapro (Abiraterone Acetate)?
A- Abirapro (Abiraterone Acetate) is an anti-cancer medication. It is a prescription medicine used in the treatment of prostate cancer in adult men. It is also used with other medications as a part of chemotherapy.
Q2- What are the storage conditions for Abirapro?
A- Store Abirapro (Abiraterone Acetate) at room temperature (10-30°C). Keep it out of reach of children and pets.
Q3- What are the common side effects of Abirapro?
A- Some of the common side effects of Abirapro are vomiting, fever, nausea, fatigue, high blood pressure, cough, diarrhea, anemia, urine infection, etc. Note that there can be other side effects also. It is advised to seek medical attention if side effects occur and disturb your daily routine.
Q4- What is the composition and strength of Abirapro?
A- The active ingredient of Abirapro is Abiraterone Acetate. It is available in the form of tablets (oral administration) in the strength of 250 mg.
Q5- How does Abirapro work?
A- Abirapro comprises Abiraterone Acetate. Abiraterone is the active metabolite of abiraterone acetate that inhibits CYP17A1. Abiraterone acetate suppresses the production of androgens. It decreases the production of testosterone in the body and is therefore used with other medications to treat prostate cancer in men.
Q6- How should I take this medicine?
A- Swallow this tablet with water. Take it exactly in the same dose and duration as prescribed by your doctor. Do not crush or chew the tablet.
Q7- What should be done in cases of overdose and missed dose?
A- In case of overdose, it is advised to seek emergency attention from a medical practitioner. However, in case of a missed dose, you can take the dose as soon as you remember. It is advised not to double the dose strength to catch up.
Q8- What are the warnings and precautionary steps?
Warning: Before the consumption of the Abirapro tablet, make sure to talk to the medical practitioner about
- Your current medical condition
- Your medical history
- Any known allergy or disease you have or ever had
- Drinking alcohol
- Driving or operating machines
Q9- Is it safe to take Abirapro during pregnancy or breastfeeding?
A- Abirapro is unsafe for use during pregnancy or breastfeeding.
Q10- Is it safe to drive after taking Abirapro?
A- It is advised to not drive or operate heavy machinery after consuming this medicine because Abirapro may cause dizziness or may affect your ability to concentrate.